Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice

Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice

Introduction: Reports have shown that the onset of diabetes mellitus (DM) in patients previously diagnosed with asthma decreases asthmatic symptoms, whereas insulin aggravates asthma. The present study evaluated the modulatory effect of insulin on the development of allergic airway inflammation in d...

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Bibliographic Details
Main Authors: Sabrina S. Ferreira, Maria A. Oliveira, Maristela Tsujita, Fernanda P. B. Nunes, Felipe B. Casagrande, Eliane Gomes, Momtchilo Russo, Wothan Tavares de Lima, Joilson O. Martins
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
allergic inflammatory reaction
asthma
diabetes mellitus
insulin
immune cell phenotyping
eosinophils
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00084/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00084/full

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