Nonstop mRNA Decay: a Special Attribute of Trans-Translation Mediated Ribosome Rescue

Nonstop mRNA Decay: a Special Attribute of Trans-Translation Mediated Ribosome Rescue

Decoding of aberrant mRNAs leads to unproductive ribosome stalling and sequestration of components of the translation machinery. Bacteria have evolved three seemingly independent pathways to resolve stalled translation complexes. The trans-translation process, orchestrated by the hybrid transfer-mes...

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Bibliographic Details
Main Authors: Krithika eVenkataraman, kip eGuja, Miguel eGarcia-Diaz, Wali eKarzai
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Microbiology
Subjects:
RNase R
tmRNA
trans-translation
SmpB
nonstop mRNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00093/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00093/full

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