Combining radiomic phenotypes of non-small cell lung cancer with liquid biopsy data may improve prediction of response to EGFR inhibitors

Abstract Among non-small cell lung cancer (NSCLC) patients with therapeutically targetable tumor mutations in epidermal growth factor receptor (EGFR), not all patients respond to targeted therapy. Combining circulating-tumor DNA (ctDNA), clinical variables, and radiomic phenotypes may improve predic...

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Bibliographic Details
Main Authors: Bardia Yousefi, Michael J. LaRiviere, Eric A. Cohen, Thomas H. Buckingham, Stephanie S. Yee, Taylor A. Black, Austin L. Chien, Peter Noël, Wei-Ting Hwang, Sharyn I. Katz, Charu Aggarwal, Jeffrey C. Thompson, Erica L. Carpenter, Despina Kontos
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88239-y