Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection.

Chronic lung infection by Pseudomonas aeruginosa is the major severe complication in cystic fibrosis (CF) patients, where P. aeruginosa persists and grows in biofilms in the endobronchial mucus under hypoxic conditions. Numerous polymorphonuclear leukocytes (PMNs) surround the biofilms and create lo...

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Bibliographic Details
Main Authors: Mette Kolpen, Michael Kühl, Thomas Bjarnsholt, Claus Moser, Christine Rønne Hansen, Lars Liengaard, Arsalan Kharazmi, Tanja Pressler, Niels Høiby, Peter Østrup Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894955?pdf=render