Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro

Host defense peptides (HDPs) show both antimicrobial and immunomodulatory properties making them important mediators of the host immune system. In humans but also in pigs many HDPs have been identified and important families such as cathelicidins and defensins have been established. In our study, we...

Full description

Bibliographic Details
Main Authors: Benoît Levast, Daniel Hogan, Jill van Kessel, Stacy Strom, Stew Walker, Jianzhong Zhu, François Meurens, Volker Gerdts
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Veterinary Science
Subjects:
PRRSV
porcine alveolar macrophages
host defense peptides
poly(I:C)
adjuvant
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2019.00233/full

Similar Items

Similar Items