The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization.

Nowadays, Enterococcus faecium is one of the leading nosocomial pathogens worldwide. Strains causing clinical infections or hospital outbreaks are enriched in the enterococcal surface protein (Esp) encoding ICEEfm1 mobile genetic element. Previous studies showed that Esp is involved in biofilm forma...

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Bibliographic Details
Main Authors: Janetta Top, Fernanda L Paganelli, Xinglin Zhang, Willem van Schaik, Helen L Leavis, Miranda van Luit-Asbroek, Tom van der Poll, Masja Leendertse, Marc J M Bonten, Rob J L Willems
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669262?pdf=render