Design, synthesis and evaluation of biological activities of some novel anti-TB agents with bio-reducible functional group
Introduction: With regard to the anti-mycobacterial activity of 2-pyrazinoic acid esters (POEs), recent studies have shown that both pyrazine core and alkyl part of POE interact with the fatty acid synthase type (I) (FAS (I)) precluding a complex formation between NADPH and FAS (I). Methods: Consid...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2019-10-01
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Series: | BioImpacts |
Subjects: | |
Online Access: | https://bi.tbzmed.ac.ir/PDF/bi-9-199.pdf |