Insulin-Regulated Aminopeptidase in Women with Breast Cancer: A Role beyond the Regulation of Oxytocin and Vasopressin

Insulin-Regulated Aminopeptidase in Women with Breast Cancer: A Role beyond the Regulation of Oxytocin and Vasopressin

Insulin-regulated aminopeptidase (IRAP) is the only enzyme known to cleave oxytocin and vasopressin; however, it is also the high-affinity binding site for angiotensin IV (AngIV) receptor type 4 (AT4) ligands and it is related to insulin-dependent glucose transporters through the translocation of th...

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Bibliographic Details
Main Authors: María Jesús Ramírez-Expósito, Basilio Dueñas-Rodríguez, María Pilar Carrera-González, Joaquín Navarro-Cecilia, Jose Manuel Martínez-Martos
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
angiotensin IV
AT4 receptor
oxytocin
BC
menopause
neoadjuvant
Online Access:https://www.mdpi.com/2072-6694/12/11/3252

Internet

https://www.mdpi.com/2072-6694/12/11/3252

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