Neuroprotective Effects of Encapsulated CNTF-Producing Cells in a Rodent Model of Huntington's Disease are Dependent on the Proximity of the Implant to the Lesioned Striatum

Huntington's disease (HD) is a devastating genetic disorder with no effective treatments for preventing or lessening the underlying neuronal degeneration. Intracerebral delivery of CNTF in animal models of HD has shown considerable promise as a means of protecting striatal neurons that would ot...

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Bibliographic Details
Main Authors: Dwaine F. Emerich, Shelley R. Winn
Format: Article
Language:English
Published: SAGE Publishing 2004-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004783983981