The role of histone H4 biotinylation in the structure of nucleosomes.

Post-translational modifications of histones play important roles in regulating nucleosome structure and gene transcription. It has been shown that biotinylation of histone H4 at lysine-12 in histone H4 (K12Bio-H4) is associated with repression of a number of genes. We hypothesized that biotinylatio...

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Bibliographic Details
Main Authors: Nina A Filenko, Carol Kolar, John T West, S Abbie Smith, Yousef I Hassan, Gloria E O Borgstahl, Janos Zempleni, Yuri L Lyubchenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3029316?pdf=render