Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia

Abstract Background Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality worldwide. Despite effective antimicrobial therapy, CAP can induce pulmonary endothelial hyperpermeability resulting in life-threatening lung failure due to an exaggerated host-pathogen interacti...

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Bibliographic Details
Main Authors: Birgitt Gutbier, Xiaohui Jiang, Kristina Dietert, Carolin Ehrler, Jasmin Lienau, Paul Van Slyke, Harold Kim, Van C. Hoang, Jason T. Maynes, Daniel J. Dumont, Achim D. Gruber, Norbert Weissmann, Timothy J. Mitchell, Norbert Suttorp, Martin Witzenrath
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Critical Care
Subjects:
Pneumococcal pneumonia
Pneumolysin
Angiopoietins
Acute lung injury
Vasculotide
Online Access:http://link.springer.com/article/10.1186/s13054-017-1851-6

Internet

http://link.springer.com/article/10.1186/s13054-017-1851-6

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