Sildenafil citrate protects skeletal muscle of ischemia-reperfusion injury: immunohistochemical study in rat model

Sildenafil citrate protects skeletal muscle of ischemia-reperfusion injury: immunohistochemical study in rat model

PURPOSE: To investigate the effect of sildenafil citrate (SC) on skeletal muscle ischemia-reperfusion (IR) injury in rats. METHODS: Adult male Wistar rats were randomized into three groups: vehicle-treated control (CTG), sildenafil citrate-treated (SCG), and sham group (SG). CTG and SCG had femoral...

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Bibliographic Details
Main Authors: Dinani Matoso Fialho de Oliveira Armstrong, Anderson da Costa Armstrong, Regina Célia Bressan Queiroz Figueiredo, Joao Eduardo Florentino, Paulo Fernandes Saad, Karen Fox-Talbot, Marc Kenneth Halushka, Dan E. Berkowitz, Murched Omar Taha, Djalma José Fagundes
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2013-04-01
Series:Acta Cirurgica Brasileira
Subjects:
Reperfusion Injury
Muscle, Skeletal
Phosphodiesterase
Inhibitors
Caspase 3
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000400008

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000400008

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