Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production

Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production

Abstract Background It is well known that ventilation with high volume or pressure may damage healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal models of acute lung injury. Melatonin exerts its beneficial effects by acting as a direct antioxidant and via me...

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Bibliographic Details
Main Authors: Geng-Chin Wu, Chung-Kan Peng, Wen-I Liao, Hsin-Ping Pao, Kun-Lun Huang, Shi-Jye Chu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Respiratory Research
Subjects:
Ventilator-induced lung injury
Melatonin receptor agonist
Ramelteon
Interleukin-10
Online Access:http://link.springer.com/article/10.1186/s12931-020-1325-2

Internet

http://link.springer.com/article/10.1186/s12931-020-1325-2

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