High-Dimensional Profiling Reveals Heterogeneity of the Th17 Subset and Its Association With Systemic Immunomodulatory Treatment in Non-infectious Uveitis

High-Dimensional Profiling Reveals Heterogeneity of the Th17 Subset and Its Association With Systemic Immunomodulatory Treatment in Non-infectious Uveitis

Background: Non-infectious uveitis (NIU) is a severe intra ocular inflammation, which frequently requires prompt systemic immunosuppressive therapy (IMT) to halt the development of vision-threatening complications. IMT is considered when NIU cannot be treated with corticosteroids alone, which is unp...

Full description

Bibliographic Details
Main Authors: Fleurieke H. Verhagen, Sanne Hiddingh, Rianne Rijken, Aridaman Pandit, Emmerik Leijten, Michel Olde Nordkamp, Ninette H. ten Dam-van Loon, Stefan Nierkens, Saskia M. Imhof, Joke H. de Boer, Timothy R. D. J. Radstake, Jonas J. W. Kuiper
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
flow cytometry
non-infectious uveitis
immunosuppressive therapy
Th17
CCR6
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02519/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02519/full

Similar Items