Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer.

Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer.

Breast cancer brain metastases (BCBM) are a challenging consequence of advanced BC. Nanoparticle agents, including liposomes, have shown enhanced delivery to solid tumors and brain. We compared pharmacokinetics (PK) and efficacy of PEGylated liposomal doxorubicin (PLD) with non-liposomal doxorubicin...

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Bibliographic Details
Main Authors: Carey K Anders, Barbara Adamo, Olga Karginova, Allison M Deal, Sumit Rawal, David Darr, Allison Schorzman, Charlene Santos, Ryan Bash, Tal Kafri, Lisa Carey, C Ryan Miller, Charles M Perou, Norman Sharpless, William C Zamboni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3641071?pdf=render

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http://europepmc.org/articles/PMC3641071?pdf=render

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