Therapeutic drug monitoring of amlodipine and the Z-FHL/HHL ratio: Adherence tools in patients referred for apparent treatment-resistant hypertension

Therapeutic drug monitoring of amlodipine and the Z-FHL/HHL ratio: Adherence tools in patients referred for apparent treatment-resistant hypertension

Background. Non-adherence to antihypertensives is a cause of ‘pseudo-treatment-resistant’ hypertension. Objective. To determine whether monitoring plasma amlodipine concentrations and inhibition of angiotensin-converting enzyme (ACE) can be adjunct adherence tools. Methods. Patients with hypertens...

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Bibliographic Details
Main Authors: E S W Jones, M Lesosky, M Blockman, S Castel, E H Decloedt, S L U Schwager, E D Sturrock, L Wiesner, B L Rayner
Format: Article
Language:English
Published: Health and Medical Publishing Group 2017-10-01
Series:South African Medical Journal
Subjects:
Amlodipine
ACE inhibitors
Therapeutic drug monitoring
Antihypertensives
Hypertension
Adherence
Online Access:http://www.samj.org.za/index.php/samj/article/view/12074

Internet

http://www.samj.org.za/index.php/samj/article/view/12074

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