Evaluation of GeneXpert PA assay compared to genomic and (semi-)quantitative culture methods for direct detection of Pseudomonas aeruginosa in endotracheal aspirates

Evaluation of GeneXpert PA assay compared to genomic and (semi-)quantitative culture methods for direct detection of Pseudomonas aeruginosa in endotracheal aspirates

Abstract Introduction Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Rapid and accurate detection of lower respiratory tract colonization and/or infection with P. aeruginosa may advise targeted preventive (antibody-based) strategies and antibiotic therapy. To inve...

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Bibliographic Details
Main Authors: Thomas Ewout van der Schalk, Jasmine Coppens, Leen Timbermont, Agata Turlej-Rogacka, Liesbet Van Heirstraeten, Matilda Berkell, Li Yu, Christine Lammens, Basil Britto Xavier, Veerle Matheeussen, Margareta Ieven, Michael McCarthy, Philippe G. Jorens, Alexey Ruzin, Mark T. Esser, Samir Kumar-Singh, Herman Goossens, Surbhi Malhotra-Kumar
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Cepheid
GeneXpert
Real-time PCR
Rapid diagnostics
VAP
Ventilator-associated pneumonia
Online Access:https://doi.org/10.1186/s13756-021-00978-9

Internet

https://doi.org/10.1186/s13756-021-00978-9

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