Denosumab Chemotherapy for Recurrent Giant-Cell Tumor of Bone: A Case Report of Neoadjuvant Use Enabling Complete Surgical Resection

Giant-cell tumor of the bone (GCTB) is a rare neoplasm that affects young adults. The tumor is generally benign but sometimes can be locally aggressive. There are no standardized approaches to the treatment of GCTB. Recently, the RANKL inhibitor denosumab has shown activity in this tumor type. We pr...

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Bibliographic Details
Main Authors: Amit Agarwal, Brandon T. Larsen, Lawrence D. Buadu, Jack Dunn, Russell Crawford, Jonathan Daniel, Maria C. Bishop
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/496351