Mycobacterium tuberculosis Pst/SenX3-RegX3 Regulates Membrane Vesicle Production Independently of ESX-5 Activity

Mycobacterium tuberculosis releases membrane vesicles (MV) that modulate host immune responses and aid in iron acquisition, although they may have additional unappreciated functions. MV production appears to be a regulated process, but virR remains the only characterized genetic regulator of vesicul...

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Bibliographic Details
Main Authors: Dylan W. White, Sarah R. Elliott, Evan Odean, Lynne T. Bemis, Anna D. Tischler
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00778-18