Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.

BACKGROUND:Recently, there has been renewed interest in the link between cholesterol and prostate cancer. It has been previously reported that in vitro, prostate cancer cells lack sterol-mediated feedback regulation of the major transcription factor in cholesterol homeostasis, sterol-regulatory elem...

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Bibliographic Details
Main Authors: James Robert Krycer, Ika Kristiana, Andrew John Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2794383?pdf=render