A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies.

Automated time-lapse microscopy can visualize proliferation of large numbers of individual cells, enabling accurate measurement of the frequency of cell division and the duration of interphase and mitosis. However, extraction of quantitative information by manual inspection of time-lapse movies is t...

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Bibliographic Details
Main Authors: Frederic D Sigoillot, Jeremy F Huckins, Fuhai Li, Xiaobo Zhou, Stephen T C Wong, Randall W King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3180452?pdf=render