Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model

Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model

Dasatinib, a new-generation Src and platelet-derived growth factor receptor (PDGFR) inhibitor, is currently under evaluation in high-grade glioma clinical trials. To achieve optimum physicochemical and/or biologic properties, alternative drug delivery vehicles may be needed. We used a novel fluorin...

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Bibliographic Details
Main Authors: Miriam Benezra, Dolores Hambardzumyan, Oula Penate-Medina, Darren R. Veach, Nagavarakishore Pillarsetty, Peter Smith-Jones, Evan Phillips, Tatsuya Ozawa, Pat B. Zanzonico, Valerie Longo, Eric C. Holland, Steven M. Larson, Michelle S. Bradbury
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800509

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http://www.sciencedirect.com/science/article/pii/S1476558612800509

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