Long-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis

Long-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis

Summary: It is generally considered that mouse embryonic stem cell (ESC) differentiation into blood cells in vitro recapitulates yolk sac (YS) hematopoiesis. As such, similar to YS-derived B-progenitors, we demonstrate here that ESC-derived B-progenitors differentiate into B-1 and marginal zone B ce...

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Bibliographic Details
Main Authors: Yang Lin, Michihiro Kobayashi, Nathalia Azevedo Portilho, Akansha Mishra, Hongyu Gao, Yunlong Liu, Pamela Wenzel, Brian Davis, Mervin C. Yoder, Momoko Yoshimoto
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119300074

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http://www.sciencedirect.com/science/article/pii/S2213671119300074

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