Visual and Biochemical Evidence of Glycocalyx Disruption in Human Dengue Infection, and Association With Plasma Leakage Severity

Visual and Biochemical Evidence of Glycocalyx Disruption in Human Dengue Infection, and Association With Plasma Leakage Severity

Background: Dengue is the most common arboviral infection globally; a minority of patients develop shock due to profound plasma leak through a disrupted endothelial barrier. Understanding of the pathophysiology underlying plasma leak is incomplete, but emerging evidence indicates a key role for degr...

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Bibliographic Details
Main Authors: Phung Khanh Lam, Angela McBride, Duyen Huynh Thi Le, Trieu Trung Huynh, Hans Vink, Bridget Wills, Sophie Yacoub
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Medicine
Subjects:
dengue
glycocalyx
microvascular
perfused boundary region
syndecan
endocan
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.545813/full

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https://www.frontiersin.org/article/10.3389/fmed.2020.545813/full

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