Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats

2,5-Hexanedione (2,5-HD) is the toxic metabolite of n-hexane which is widely used as solvent in numerous industries. The present study elucidated the precise mechanism of 2,5-HD in hepatorenal toxicity by determining the involvement of oxidative stress in rats. Adult male Wistar rats were exposed to...

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Bibliographic Details
Main Authors: Isaac A. Adedara, Amos O. Abolaji, Blessing E. Odion, Isioma J. Okwudi, Abiola A. Omoloja, Ebenezer O. Farombi
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2014/239240