Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma.

Targeting and inhibiting DNA repair pathways is a powerful strategy of controlling malignant growth. One such strategy includes the inhibition of PARP1, a central element in the intracellular DNA damage response. To determine and visualize the expression and intercellular distribution of PARP1 in vi...

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Bibliographic Details
Main Authors: Susanne Kossatz, Wolfgang A Weber, Thomas Reiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4726809?pdf=render