The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes

The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes

BackgroundThe pathogenesis of type 1 diabetes (T1D) involves complex genetic susceptibility that impacts pathways regulating host immunity and the target of autoimmune attack, insulin-producing pancreatic β-cells. Interactions between risk variants and environmental factors result in significant het...

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Bibliographic Details
Main Authors: Robert C. Sharp, Matthew E. Brown, Melanie R. Shapiro, Amanda L. Posgai, Todd M. Brusko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
CD47
SIRPG
SIRPA
SIRPB1
type 1 diabetes
signal regulatory protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.739048/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.739048/full

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