New insights into the mechanisms of embryonic stem cell self-renewal under hypoxia: a multifactorial analysis approach.

Previous reports have shown that culturing mouse embryonic stem (mES) cells at different oxygen tensions originated different cell proliferation patterns and commitment stages depending on which signaling pathways are activated or inhibited to support the pluripotency state. Herein we provide new in...

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Bibliographic Details
Main Authors: Hélder S C Barbosa, Tiago G Fernandes, Tiago P Dias, Maria Margarida Diogo, Joaquim M S Cabral
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3372480?pdf=render