Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates.

Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates.

Oligomeric amyloid β (Aβ) is currently considered the most neurotoxic form of the Aβ peptide implicated in Alzheimer's disease (AD). The molecular structures of the oligomers have remained mostly unknown due to their transient nature. As a result, the molecular mechanisms of interactions betwee...

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Bibliographic Details
Main Authors: Massih Khorvash, Nick Blinov, Carol Ladner-Keay, Jie Lu, Judith M Silverman, Ebrima Gibbs, Yu Tian Wang, Andriy Kovalenko, David Wishart, Neil R Cashman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232266

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https://doi.org/10.1371/journal.pone.0232266

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