High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells

High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells

Metformin, the most widely prescribed anti-diabetic drug, is shown to possess anti-cancer potential in treatment of cancers, including breast cancer; decreases breast cancer risk; and improves overall survival. However, reports suggest that higher glucose concentrations may negatively impact the ant...

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Bibliographic Details
Main Authors: Sharon Varghese, Samson Mathews Samuel, Elizabeth Varghese, Peter Kubatka, Dietrich Büsselberg
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
anti-cancer therapy
breast cancer
hyperglycemia/diabetes
metformin
triple negative breast cancers
Online Access:http://www.mdpi.com/2218-273X/9/1/16

Internet

http://www.mdpi.com/2218-273X/9/1/16

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