Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.

Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.

There is an urgent need for the development of new, improved vaccine adjuvants against T. spiralis infection. Polysaccharides are effective, safe, and biodegradable as adjuvant. In our study, we first observed the protective efficacy of lentinan as adjuvant against helminth T. spiralis infection. Re...

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Bibliographic Details
Main Authors: Xuemin Jin, Xiaolei Liu, Jing Ding, Lixiao Zhang, Yaming Yang, Xuelin Wang, Yong Yang, Mingyuan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008632

Internet

https://doi.org/10.1371/journal.pntd.0008632

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