Direct Evidence of Endothelial Dysfunction and Glycocalyx Loss in Dermal Biopsies of Patients With Chronic Kidney Disease and Their Association With Markers of Volume Overload

Direct Evidence of Endothelial Dysfunction and Glycocalyx Loss in Dermal Biopsies of Patients With Chronic Kidney Disease and Their Association With Markers of Volume Overload

Cardiovascular morbidity is a major problem in patients with chronic kidney disease (CKD) and endothelial dysfunction (ED) is involved in its development. The luminal side of the vascular endothelium is covered by a protective endothelial glycocalyx (eGC) and indirect evidence indicates eGC loss in...

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Bibliographic Details
Main Authors: Josephine Koch, Ryanne S. Hijmans, Manuela Ossa Builes, Wendy A. Dam, Robert A. Pol, Stephan J. L. Bakker, Hendri H. Pas, Casper F. M. Franssen, Jacob van den Born
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CKD
endothelial dysfunction
NT-proBNP
inflammation
sodium
glycocalyx
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.733015/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.733015/full

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