Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"

Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"

<p>Abstract</p> <p>The assessment of cellular anti-viral immunity is often hampered by the limited availability of adequate samples, especially when attempting simultaneous, high-resolution determination of T cell responses against multiple viral infections. Thus, the development o...

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Bibliographic Details
Main Authors: Wong Johnson T, Suscovich Todd J, Linde Caitlyn, Henry Leah M, Hewitt Hannah S, Chisholm John V, Loggi Elisabetta, Bihl Florian K, Frahm Nicole, Andreone Pietro, Brander Christian
Format: Article
Language:English
Published: BMC 2005-05-01
Series:Journal of Translational Medicine
Subjects:
Cytotoxic T Cells
HIV
EBV
CMV
HCV
HBV
CTL
epitope
peptide
cell expansion
anti-CD3
ELISpot
peptide matrix
Online Access:http://www.translational-medicine.com/content/3/1/20

Internet

http://www.translational-medicine.com/content/3/1/20

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