Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

Acute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome (ARDS) are well-known illnesses. Uncontrolled and self-amplified pulmonary inflammation lies at the center of the pathology of this disease. Emodin, the bio-active coxund of herb Radix rhizoma Rhei, shows pot...

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Bibliographic Details
Main Authors: Min Xiao, Tao Zhu, Wei Zhang, Tao Wang, Yong-Chun Shen, Qiong-Fang Wan, Fu-Qiang Wen
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:International Journal of Molecular Sciences
Subjects:
emodin
acute lung injury (ALI)
acute respiratory distress syndrome (ARDS)
lipopolysaccharide (LPS)
E-selectin
MCP-1
nuclear factor-κB (NF-κB)
Online Access:http://www.mdpi.com/1422-0067/15/11/19355

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http://www.mdpi.com/1422-0067/15/11/19355

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