Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress

Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress

Abstract Upregulation of histone acetylation plays a critical role in the dysregulation of transcription. It alters the structure of chromatin, which leads to the onset of cancer. Histone deacetylase inhibitors may therefore be a promising way to limit cancer progression. In this study, we examined...

Full description

Bibliographic Details
Main Authors: Ying Huang, Wuping Yang, Huihong Zeng, Chuan Hu, Yaqiong Zhang, Nanhua Ding, Guangqin Fan, Lijian Shao, Bohai Kuang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Droxinostat
HT-29 cells
Apoptosis
ROS
Online Access:http://link.springer.com/article/10.1186/s11658-018-0101-5

Internet

http://link.springer.com/article/10.1186/s11658-018-0101-5

Similar Items