Lactobacillus reuteri Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota

Lactobacillus reuteri Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota

The gut microbiome plays an important role in immune function and has been implicated in multiple sclerosis (MS). However, how and if the modulation of microbiota can prevent or treat MS remain largely unknown. In this study, we showed that probiotic Lactobacillus reuteri DSM 17938 (L. reuteri) amel...

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Bibliographic Details
Main Authors: Baokun He, Thomas K. Hoang, Xiangjun Tian, Christopher M. Taylor, Eugene Blanchard, Meng Luo, Meenakshi B. Bhattacharjee, Jasmin Freeborn, Sinyoung Park, Jacob Couturier, John William Lindsey, Dat Q. Tran, Jon Marc Rhoads, Yuying Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
experimental autoimmune encephalomyelitis
Lactobacillus reuteri
TH1/TH17 cells
IFN-γ/IL-17
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00385/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00385/full

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