Double positive CD4+CD8+ T cells: key suppressive role in the production of autoantibodies in systemic lupus erythematosus

Background & objectives: The presence of CD4+CD8+ (double positive) T cells (DPT) in the target organs of several autoimmune diseases has been reported. The aim of this study was to investigate the pathogenic role of DPT in systemic lupus erythematosus (SLE). Methods: A total of 175 SLE cases a...

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Bibliographic Details
Main Authors: Yongkang Wu, Bei Cai, Weihua Feng, Bin Yang, Zhuochun Huang, Chuan Zuo, Lanlan Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Medical Research
Subjects:
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=140;issue=4;spage=513;epage=519;aulast=Wu