Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK

Anorexia nervosa (AN) is an eating disorder leading to malnutrition and, ultimately, to energy wasting and cachexia. Rodents develop activity-based anorexia (ABA) when simultaneously exposed to a restricted feeding schedule and allowed free access to running wheels. These conditions lead to a life-t...

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Bibliographic Details
Main Authors: Angela Fraga, Eva Rial-Pensado, Rubén Nogueiras, Johan Fernø, Carlos Diéguez, Emilio Gutierrez, Miguel López
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.669980/full