Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO<sub>2</sub> E171 in Male and Female Rat Pups

Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO<sub>2</sub> E171 in Male and Female Rat Pups

Oral exposure to nanoparticles (NPs) during early life is an understudied area. The goals of this study were to evaluate the effect of pre-weaned rat gastric fluids on 50 nm CuO NPs and TiO<sub>2</sub> E171 in vitro, and to evaluate uptake in vivo. The NP uptake was studied in vivo in ma...

Full description

Bibliographic Details
Main Authors: Ninell P. Mortensen, Maria Moreno Caffaro, Shyam Aravamudhan, Lakshmi Beeravalli, Sharmista Prattipati, Rodney W. Snyder, Scott L. Watson, Purvi R. Patel, Frank X. Weber, Stephanie A. Montgomery, Susan J. Sumner, Timothy R. Fennell
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nanomaterials
Subjects:
rat pups
simulated gastric digestion
tissue uptake
ENM stability
CuO nanoparticles
food grade TiO<sub>2</sub> E171
Online Access:https://www.mdpi.com/2079-4991/11/6/1487

Internet

https://www.mdpi.com/2079-4991/11/6/1487

Similar Items