A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium–Host Interaction
As a major effector of the ESX-1 secretion system, EsxA is essential for the virulence of pathogenic mycobacteria, such as <i>Mycobacterium tuberculosis</i> (Mtb) and <i>Mycobacterium marinum</i> (Mm). EsxA possesses an acidic pH-dependent membrane permeabilizing activity and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/10/7/1645 |