Zingerone produces antidiabetic effects and attenuates diabetic nephropathy by reducing oxidative stress and overexpression of NF-κB, TNF-α, and COX-2 proteins in rats

Zingerone produces antidiabetic effects and attenuates diabetic nephropathy by reducing oxidative stress and overexpression of NF-κB, TNF-α, and COX-2 proteins in rats

Diabetes mellitus (DM) is characterized by impaired insulin secretion or utilization, accompanied by hyperglycemia and glycosuria, as well as by a plethora of DM-induced complications, including nephropathy. The purpose of this investigation was 2-fold: to evaluate the antidiabetic potential of zing...

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Bibliographic Details
Main Authors: Brahmjot Singh, Ajay Kumar, Hasandeep Singh, Sarabjit Kaur, Satwinderjeet Kaur, Harpal Singh Buttar, Saroj Arora, Balbir Singh
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Journal of Functional Foods
Subjects:
Zingerone
Diabetes mellitus
Diabetic nephropathy
Oxidative stress
NF-kB
TNF-α
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620304230

Internet

http://www.sciencedirect.com/science/article/pii/S1756464620304230

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