Mechanism of ad5 vaccine immunity and toxicity: fiber shaft targeting of dendritic cells.
Recombinant adenoviral (rAd) vectors elicit potent cellular and humoral immune responses and show promise as vaccines for HIV-1, Ebola virus, tuberculosis, malaria, and other infections. These vectors are now widely used and have been generally well tolerated in vaccine and gene therapy clinical tri...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-02-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1803013?pdf=render |