Expression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coli.

Sialyltransferases (STs) are disulfide-containing, type II transmembrane glycoproteins that catalyze the transfer of sialic acid to proteins and lipids and participate in the synthesis of the core structure oligosaccharides of human milk. Sialic acids are found at the outermost position of glycostru...

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Bibliographic Details
Main Authors: Maria Elena Ortiz-Soto, Jürgen Seibel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4864186?pdf=render