Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS

Abstract Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular...

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Bibliographic Details
Main Authors: Giovanna Morello, Maria Guarnaccia, Antonio Gianmaria Spampinato, Salvatore Salomone, Velia D’Agata, Francesca Luisa Conforti, Eleonora Aronica, Sebastiano Cavallaro
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46355-w