Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy

Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy

Background Multiple synergistic combination approaches with cancer drugs are developed to overcome primary resistance to immunotherapy; however, the mechanistic rationale to combine chemoradiotherapy (CRT) with immune checkpoint inhibitors remains elusive.Methods This study described the immunologic...

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Bibliographic Details
Main Authors: Florence Marliot, Marc Van den Eynde, Franck Pagès, Romain Boidot, Céline Mirjolet, Amos Kirilovsky, Carine El Sissy, Nacilla Haicheur-Adjouri, Viorel Scripcariu, Olivier Adotevi, Laurie Spehner, Elodie Lauret Marie Joseph, Benoît Lecoester, Laura Boullerot, Laurie Rangan, Amélie Marguier, Florent Tochet, Magalie Dosset, Jihane Boustani, Patrice Ravel, Jean-René Pallandre, Francis Bonnefoy, Emmanuel Cornillot
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/7/e002256.full

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https://jitc.bmj.com/content/9/7/e002256.full

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