Activation of protease-activated receptor 2 induces VEGF independently of HIF-1.

<h4>Background</h4>Human adipose stem cells (hASCs) can promote angiogenesis through secretion of proangiogenic factors such as vascular endothelial growth factor (VEGF). In other cell types, it has been shown that induction of VEGF is mediated by both protease activated receptor 2 (PAR2...

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Bibliographic Details
Main Authors: Jeppe Grøndahl Rasmussen, Simone Elkjær Riis, Ole Frøbert, Sufang Yang, Jens Kastrup, Vladimir Zachar, Ulf Simonsen, Trine Fink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23049945/pdf/?tool=EBI