The scavenger receptor CD36 contributes to the neurotoxicity of bone marrow-derived monocytes through peroxynitrite production

The scavenger receptor CD36 contributes to the neurotoxicity of bone marrow-derived monocytes through peroxynitrite production

CD36, a class B scavenger receptor present in microglia, endothelium and leukocytes, plays a key role in ischemic brain injury by promoting the expression of inflammatory genes and production of reactive oxygen species (ROS). However, it is not known whether ischemic brain damage is mediated by CD36...

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Bibliographic Details
Main Authors: Ping Zhou, Liping Qian, Eduardo F. Gallo, Ruba S. Deeb, Josef Anrather, Steven S. Gross, Costantino Iadecola
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Neurobiology of Disease
Subjects:
CD36
Hippocampal slice
Bone marrow-derived monocytes-macrophages
Oxidative and nitrative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000313

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http://www.sciencedirect.com/science/article/pii/S0969996111000313

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