Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites

Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites

Summary: Tight regulation of neuronal transport allows for cargo binding and release at specific cellular locations. The mechanisms by which motor proteins are loaded on vesicles and how cargoes are captured at appropriate sites remain unclear. To better understand how KIF1A-driven dense core vesicl...

Full description

Bibliographic Details
Main Authors: Riccardo Stucchi, Gabriela Plucińska, Jessica J.A. Hummel, Eitan E. Zahavi, Irune Guerra San Juan, Oleg Klykov, Richard A. Scheltema, A.F. Maarten Altelaar, Casper C. Hoogenraad
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718309987

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718309987

Similar Items