Organotypic brain slice cultures of adult transgenic P301S mice--a model for tauopathy studies.

BACKGROUND: Organotypic brain slice cultures represent an excellent compromise between single cell cultures and complete animal studies, in this way replacing and reducing the number of animal experiments. Organotypic brain slices are widely applied to model neuronal development and regeneration as...

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Bibliographic Details
Main Authors: Agneta Mewes, Heike Franke, David Singer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3439393?pdf=render