SIRT3 in cardiac physiology and disease

Functional defects in mitochondrial biology causally contribute to various human diseases, including cardiovascular disease. Impairment in oxidative phosphorylation, mitochondrial oxidative stress and increased opening of the mitochondrial permeability transition pore add to the underlying mechanism...

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Bibliographic Details
Main Authors: Christoph Koentges, Christoph Bode, Heiko Bugger
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00038/full