SIRT3 in cardiac physiology and disease
Functional defects in mitochondrial biology causally contribute to various human diseases, including cardiovascular disease. Impairment in oxidative phosphorylation, mitochondrial oxidative stress and increased opening of the mitochondrial permeability transition pore add to the underlying mechanism...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-10-01
|
Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00038/full |